If you have clicked on this page, it means that you are as well tired of the irritating mice in your home. Just know that you’re not alone!
These little critters can infest your home and multiply at an alarming rate. Before you know it, your food and other things in the house will be destroyed. But since you are here, you can be guaranteed the problem is solved. If you are looking for the best mouse poison that really works then check below the list.Best Mouse Poison

Related: Top 10 Best Rat Poison Reviews (Do It Yourself & Avoid Expert Cost)

Our Recommended Best Mouse Poison Comparison Chart

ImagesMouse PoisonOur RatingPrice Idea
Best Choice

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D-Con Ready Mix Bait Bits For Mice Brodifacoum Mice
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98 out of 100High
Farmar Choice

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Havoc Rat & Mouse Bait
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97 out of 100Medium

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D-Con Ready Mix Rat and Mouse Killer, 2-12 Oz boxes, 8 Bait Trays [2 Boxes of 4 Bait Trays]
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98 out of 100High
Check PriceJust One Bite Ii Bars Mice And Rat Killer,8lbs(8, 16 oz bars)
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96 out of 100Medium

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D-Con Mouse Prufe II 4 Pack - 1.5 oz each
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97 out of 100High

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MOTOMCO Tomcat Mouse and Rat Liquid Concentrated Bait, 1.68-Ounce, (8 Pack)
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94 out of 100Low

Even though there are lots of mice poisons on the market, not all of them get the job done. The mouse poisons that we’re going to discuss in this post have been tested and proven to offer outstanding results. Go through them and choose the one you’re comfortable with.

6 Best Mouse Poison Reviews 2020

We have selected top rated 6 mouse poison that really works.

D Con Ready Mix Baits, 3.oz

After using different types of mouse killers, I can gladly say that D con ready mix is one of the best. This mouse poison is very effective in reducing or eliminating the mouse population in your home. It comes with brodifacoum as the active ingredient. This second generation anticoagulant is extremely effective and it kills in only one feeding. The D con ready mix comes with 4 trays for placing bait in areas of rodent activity.
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The formula that the D con contains is very strong and can kill even warfarin-resistant rats. After consuming the pellets, the mouse will die after a few days. The only challenge you will face is that there will be an odor that you will have to put up for some days before the rats decay completely. This depends if they will die in the walls, ceiling, or in their nesting areas where you can’t reach them and dispose of. Be ready to spend as this mouse killer is quite expensive when compared to other brands.


  • It kills mice and rats
  • It has brodifacoum which is a very potent anticoagulant
  • Kills in just one feeding
  • Comes with 4 ready to use trays
  • It functions as stated


  • It is quite expensive
  • Not the best for large rats

Related: Havoc Rat & Mouse Poison Reviews

Havoc Rat and Mouse Bait

The Havoc rat and mouse bait are suitable for agricultural buildings, commercial areas, and home use. When you use this product, you will be guaranteed to clear the entire mice problem in your surrounding as it can be used both indoors and outdoors. When you use it outside, ensure to place it in bait stations so that pets and other untargeted animals don’t feed on it. It contains brodifacoum, which is a second generation anticoagulant and the mouse has to just feed on it once for the effect to take place. The rat or mouse will days a few days after consuming on the bait.
Havoc Rat and Mouse BaitCheck Price

The powerful pellets take effect immediately the mouse feeds on the poisonous bait. No matter the type of rats, be it warfarin-resistant, roof rats or house mice, this best mouse poison will get the job done. Just one night of feeding is enough to eliminate the rats and mice in your compound.


  • It is convenient and ready to use
  • It kills very effectively as it contains brodifacoum as the active ingredient
  • One feed is enough to kill the rodent
  • They are good for both indoor and outdoor use
  • It contains ingredients and attractants for easy baiting of rats and mice


  • Some users have reported that mice don’t eat the bait but walks over it

D-Con Ready Mix Rat and Mouse Killer, 2x12oz boxes

This D Con ready mix rat and mouse killer is different from the first one in that it comes with two packs, instead of one. So, if you have a large rat or mice infestation in your home, then this package will be enough to eliminate all of them. It also has brodifacoum as the active ingredient. Therefore, the mice will suffocate in just one feeding. Strategically place the trays in rodent activity areas so that they can feed on the bait. The mouse will die within 4 to 5 days after feeding on the bait.
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The D Con ready mix is very effective in eliminating rodents with warfarin-resistant rats and warfarin-resistant mice included. This is a quality product as it is made in the USA, but it is also quite expensive.


  • Has the ability to kill in one feeding
  • Easy to use and bait rodents
  • Very effective in eliminating rats and mice
  • It comes with trays for placing bait
  • Kills warfarin resistant rats and warfarin resistant house mice
  • It is made in the USA


  • Not the best to use where kids and pets are
  • It is quite expensive

Just One Bite Li Bars Mice and Rat Killer

The Just one bite Li bars mice and rat killer is one of the most effective rodent killers that you will find on the market. It can be used both indoors and outdoors. Inside the house, you can scatter them in rodent activity areas. And if you use them outside, you can use wires to tie them so that they’re not stolen. The bars contain bromadiolone which eliminates the rats and mice in just one feed. The mice will die almost instantly or after a few days.
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Just like its name, Just One Bite Li bar is a very lethal killer and will even eliminate rodents like squirrels, voles, and chipmunks from your agricultural building. Since it is very powerful, you should use it away from kids and pets as they can get hurt when they have a taste of the bar.


  • They are very effective
  • Kills in just one feeding
  • Good for eliminating a large population
  • The bait blocks are extremely durable and cannot be moved with much ease
  • It contains a formula that attracts and kills quickly
  • Kills all kinds of rats and mice
  • Functions as stated


  • Not the best to use around pets or kids

D-con Mouse Prufe II mouse killer

Similar to other D Con products, the D Con mouse prufe II killer is a fully functional product. It is highly effective in eliminating both rat and mice population. It comes in form of pellets which can be easily placed in hard to reach areas like corners and in attics. Additionally, it contains brodifacoum which is one of the best formulas for killing rodents. Just one feeding is enough to suffocate the mouse almost instantly, and the mice after some days.
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D Con mouse prufe II will bring peace in your home as it can be scattered even in the hard to reach areas where the critters are hiding. So, no mice will be spared at all. Moreover, it will kill all kinds of rats and mice with warfarin-resistant house mice included. Keep it out of reach of kids and pets.


  • This prufe kills in just one dose
  • It contains brodifacoum which is a potent formula
  • It functions effectively in eliminating mice
  • Fits well in difficult to reach places like in corners
  • They are extremely reliable in eliminating critters


  • It is expensive when compared to other baits
  • It is very dangerous and can harm pets and children

Motomco Tomcat Mouse and Rat Bait

If you’ve tried out different solid baits and have not helped you in eliminating the mouse problem in your home, then you should try out this Motomco liquid concentrated rat and mouse poison. Tomcat rat poison kill almost all types of harmful rodents. If rats don’t eat, they will drink. So, this is a good alternative to baits as the mice will come to have a drink and then suffocate to death slowly.
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The liquid concentrate needs to be mixed with water for it to be effective. It contains diphacinone as the active ingredient. This kills slowly and the rat or mice have to drink more for it to be effective. To get great results, use the liquid bait in dry conditions. You should keep the bait out of reach of children and pets as they can suffocate if they have a drink of the poison.


  • It contains diphacinone as the active ingredient
  • This bait is extremely effective in dry conditions
  • It takes time but works as stated


  • It evaporates if it stays long without being used
  • You will be forced to buy a liquid dispenser separately which will prove to be costly in the long run


Question: When is the best time to start placing the baits for the mouse to feed on?
Answer: Start to place bait immediately you notice mouse activity. Look for areas with rodent activity or where you suspect the mouse to reside. Normally, mice tend to travel around 10 to 30 feet from their nestling. Ensure that the bait is fresh and free from contaminants like chemicals. Also, check the bait station and change it or replenish it regularly.

Question: How do I prevent kids and pets from accessing the poisonous mouse bait?
Answer: Use baiting stations with a lockable feature. This way, only targeted rodents will suffocate from eating the bait. Bait stations are tamper-resistant, durable, and can be attached to ensure that they are not moved or messed with.

Question: Is one feeding enough for the mice to die?
Answer: It depends on the type of rodenticide that you’re using. If it’s a first-generation anticoagulant, then you will have to feed the mice multiple times for it to be effective. But if it’s a second-generation anticoagulant, just one feed is enough for them to suffocate to death. Mice die quicker than rats as they are smaller and the impact is far much stronger.

If you still have any questions after reading this best mouse poison, then comment below.

  1. Mary Pierce says:

    Can this be sprayed under hood of vehicles

    1. Fred Mills says:


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