Best Mouse Poison of 2021: Effectively Kill the Mice

If you have clicked on this page, it means that you are as well tired of the irritating mice in your home. Just know that you’re not alone! These little critters can infest your home and multiply at an alarming rate. Before you know it, your food and other things in the house will be destroyed. But since you are here, you can be guaranteed the problem is solved. If you are looking for the best mouse poison that really works, then check below the list.Best Mouse Poison

Our Recommended Most Effective Mouse Poison Comparison Chart

ImagesTop 3 Mouse PoisonProduct Details
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MOTOMCO Tomcat Mouse and Rat Liquid Concentrated Bait, 1.68-Ounce, (8 Pack)
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  • Effective liquid poison bait ideal for use in outdoor areas

  • Active ingredients: Diphacinone

  • Product Weight: 0.1 Pounds

  • Low price
  • Farmar Choice

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    Havoc Rat & Mouse Bait
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  • Ready-to-use pellets can be placed both in buildings and commercial areas

  • Strongest anticoagulant capable of killing big Norway rats

  • Active ingredients: Brodifacoum

  • Product Weight: 10 Pounds

  • Medium price
  • Affordable Choice

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    D-Con Ready Mix Bait Bits For Mice Brodifacoum Mice
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  • You can setup this Tamper proof bait station in all weather conditions

  • Active ingredients: Brodifacoum

  • Product Weight: 0.3 pounds

  • Lowest price


  • Even though there are lots of rat poisons on the market, not all of them get the job done. The mouse poisons that we’re going to discuss in this post have been tested and proven to offer outstanding results. Go through them and choose the one you’re comfortable with.

    6 Best Mouse Poison Reviews 2020

    We have selected six top-rated Mice poisons that really work.

    D Con Ready Mix Bait Rat Poison

    After using different types of mouse killers, I can gladly say that the D con ready mix is one of the best. This mouse poison is very effective in reducing or eliminating the mouse population in your home. It comes with brodifacoum as the active ingredient. This second-generation anticoagulant is extremely effective, and it kills in only one feeding. The D con ready mix comes with 4 trays for placing bait in areas of rodent activity.

    Technical Features of d-CON Corner Fit – 1 bait station:

    Features D Con Ready Mix Mice Bait, 3. oz
    Kills: multiple mice
    Tamper-resistant to kids: Yes
    Design: Corner Fit
    Safe around dogs and cats: Yes
    Can be Used Outdoors: Yes
    Comes with: Four ready to use trays
    Weight: 4.6 ounces
    Dimensions: 1.5 x 5.38 x 3.38 inches
     Simple to use: Yes
    Weather-resistant: Yes

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    The formula that the D con contains is very strong and can kill even warfarin-resistant rats. After consuming the pellets, the mouse will die after a few days. The only challenge you will face is that there will be an odor that you will have to put up for some days before the rats decay completely. This depends if they will die in the walls, ceiling, or in their nesting areas where you can’t reach them and dispose of them. Be ready to spend as this mouse killer is quite expensive when compared to other brands.

    Pros:

    • It kills mice and rats
    • The rat killer has brodifacoum which is a very potent anticoagulant
    • It kills in just one feeding
    • This rat poison comes with 4 ready to use trays
    • It functions as stated
    • D-con kills faster than Tomcat 

    Cons:

    • Inhumane. Use electric mouse traps to kill them humanely
    • Not the best for large rats

    Havoc Rat and Mouse Poison Safe for Dogs and Pets

    The Havoc rat and mouse bait are suitable for agricultural buildings, commercial areas, and home use. When you use this product, you will be guaranteed to clear the entire mice problem in your surrounding as it can be used both indoors and outdoors. When you use it outside, ensure to place it in bait stations so that pets and other untargeted animals don’t feed on it. It contains brodifacoum, which is a second-generation anticoagulant, and the mouse has to just feed on it once for effect to take place. The rat or mouse will die a few days after consuming the bait.

    Technical Features of Neogen Havoc Rodenticide Rat & Mouse Bait Pellet Pack:

    Features Havoc rat and mouse bait
    Available in: mouse poison pellets, bait blocks, and Meal Bait configurations
    May kill: rats and mice in a single night’s feeding
    Proven active ingredient:  brodifacoum
    Safe around dogs and cats: Yes
    Convenient and ready to use: Yes
    Both indoor and outdoor use: Yes
    Weight: 9.25 pounds
    Dimensions: 21.25 x 10 x 19.5 inches
    Contains: ingredients and attractants for easy baiting of rats and mice
    Weather-resistant: Yes

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    The powerful pellets take effect immediately the mouse feeds on the poisonous bait. No matter the type of rats, be it warfarin-resistant, roof rats, or house mice, this best mouse poison will get the job done. Just one night of feeding is enough to eliminate the rats and mice in your compound.

    Pros:

    • It is convenient and ready to use
    • The rodenticide is more effective compared to homemade rat poisons
    • The strongest mouse poison works in 2-3 days
    • It kills very effectively as it contains brodifacoum as the active ingredient
    • One feed is enough to kill the rodent as it will damage the central nervous system
    • They are good for both indoor and outdoor use
    • You don’t need to worry if the dog eats mouse poison
    • It contains ingredients and attractants for easy baiting of rats and mice

    Cons:

    • Some users have reported that mice don’t eat the bait but walk over it.
    • You have to remove the dead rodents immediately. 

    D-Con Ready Mix Rat and Mouse Killer, 2x12oz boxes

    This D Con ready mix rat and mouse killer are different from the first one in that it comes in two packs instead of one. So, if you have a large rat or mice infestation in your home, then this package will be enough to eliminate all of them. It also has brodifacoum as the active ingredient. Therefore, the mice will suffocate in just one feeding. Strategically place the trays in rodent activity areas so that they can feed on the bait. The mouse will die within 4 to 5 days after feeding on the bait.

    Technical Features of d-Con Disposable Corner Fit Mouse Poisons & Bait Stations:

    Features D Con ready mix rat and mouse killer
    Tamper Resistant: Yes
    Use: indoors only
    Ideal for:  corners, attics, behind appliances, basements, garages, and sheds
    Mouse Dies in its Nest: Yes
    Child Resistant: Yes
    No Rodent Contact: Yes
    Pre-Baited & Ready to Use: Yes
    Disposable: Yes
    Dimensions: 1.5 x 8.8 x 9.5 inches
    Weight: 5.93 Ounces

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    The D Con ready mix is very effective in eliminating rodents with warfarin-resistant rats, and warfarin-resistant mice included. This is a quality product as it is made in the USA, but it is also quite expensive.

    Pros:

    • Has the ability to kill mice in one feeding
    • Easy to use and bait rodents
    • Very effective in eliminating rats and mice
    • It comes with trays for placing bait
    • It stops rodent infestation within a week
    • The poison kills warfarin resistant rats and warfarin resistant house mice
    • It is made in the USA

    Cons:

    • Not the best to use where kids and pets are
    • It is quite expensive

    Just One Bite Li Bars Mice and Rat Killer

    The Just one bite Li bars mice and rat killer is one of the most effective rodent killers that you will find on the market. It can be used both indoors and outdoors. Inside the house, you can scatter them in rodent activity areas. And if you use them outside, you can use wires to tie them so that they’re not stolen. The bars contain bromadiolone which eliminates the rats and mice in just one feed. The mice will die almost instantly or after a few days.

    Technical Features of d-Con Disposable Corner Fit Mouse Poison Bait Station:

    Features D Con ready mix rat and mouse killer
    Dimensions: 19 x 16 x 9 inches
    Weight: 10.56 Ounces
    Death is delayed : 4 to 5 days
    Kills: warfarin resistant Norway rats
    Good for: eliminating a large population
    Extremely durable: Yes
    Kills in just one feeding: Yes
    Use it away from kids and pets: Yes
    Active Ingredients: Bromadiolone
    Has:  nibble ridges

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    Just like its name, Just One Bite Li bar is a very lethal killer and will even eliminate rodents like squirrels, voles, and chipmunks from your agricultural building. Since it is very powerful, you should use it away from kids and pets as they can get hurt when they have a taste of the bar.

    Pros:

    • They are very effective
    • Just one bite bait block kills in just one feeding
    • Good for eliminating a large population
    • The mouse poison blocks are extremely durable and cannot be moved with much ease
    • It contains a formula that attracts and kills quickly
    • It kills rats, mice, and other rodents
    • The flavor attract rodents easily

    Cons:

    D-con Mouse Prufe II mouse killer

    Similar to other D Con products, the D Con mouse Prufe II killer is a fully functional product. It is highly effective in eliminating both rat and mice populations. It comes in the form of pellets which can be easily placed in hard-to-reach areas like corners and in attics. Additionally, it contains brodifacoum which is one of the best formulas for killing rodents. Just one feeding is enough to suffocate the mouse almost instantly, and the mice after some days.

    Technical Features of d-Con Disposable Corner Fit Mice Poison:

    Features D-con Mouse Prufe II mouse killer
    Mouse Dies in its Nest: Yes
    Use: indoors only
    Ideal for: corners, attics, behind appliances, basements, garages, and sheds
    Tamper Resistant: Yes
    Pre-Baited & Ready to Use: Yes
    No Rodent Contact: Yes
    Child Resistant: No
    Disposable: Yes
    Dimensions: 1.5 x 8.8 x 9.5 inches
    Weight: 5.93 Ounces

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    D Con mouse Prufe II will bring peace to your home as it can be scattered even in the hard-to-reach areas where the critters are hiding. So, no mice will be spared at all. Moreover, it will kill all kinds of rats and mice with warfarin-resistant house mice included. Keep it out of reach of kids and pets.

    Pros:

    • This Prufe kills mice in just one dose
    • It contains brodifacoum which is a potent formula
    • The rodenticide functions effectively in eliminating mice
    • It fits well in difficult to reach places like in corners
    • The poisoned mouse will die in 3-4 days
    • They are extremely reliable in eliminating critters

    Cons:

    • It is expensive when compared to other rat poison baits
    • It is very dangerous and can harm pets and children if they ingested mouse poison

    Motomco Tomcat Mouse and Rat Baits

    If you’ve tried out different solid baits and have not helped you in eliminating the mouse problem in your home, then you should try out this Motomco liquid concentrated rat and mouse poison. Tomcat rat poison kills almost all types of harmful rodents. If rats don’t eat, they will drink. So, this is a good alternative to baits as the mice will come to have a drink and then suffocate to death slowly.

    Technical Features of MOTOMCO Tomcat Mouse and Rat Liquid Concentrated Bait, 1.68-Ounce:

    Features Motomco Tomcat Mouse and Rat Bait
    Active ingredient: Diphacinone
    Use: indoors only
    Effective liquid bait: for the pest control of both rats and mice
    Not for use: in residential settings
    It takes time: Yes
    Age Range: All Life Stages
    Item Form: Liquid
    Do not use outdoors: Yes
    Volume: 13.44 Fluid Ounces
    Weight: 1.68 oz.

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    The liquid concentrate needs to be mixed with water for it to be effective. It contains Diphacinone as the active ingredient. This kills slowly, and the rat or mice have to drink more for it to be effective. To get great results, use the liquid bait in dry conditions. You should keep the bait out of reach of children and pets as they can suffocate if they have a drink of the poison.

    Pros:

    • It contains Diphacinone as the active ingredient
    • This bait is extremely effective in dry conditions
    • It takes time but works as stated

    Cons:

    • It evaporates if it stays long without being used
    • You will be forced to buy a liquid dispenser separately, which will prove to be costly in the long run

    FAQ

    Question: When is the best time to start placing the mouse poison baits for the mouse to feed on?
    Answer: Start to place bait immediately you notice mouse activity. Look for areas with rodent activity or where you suspect the mouse to reside. Normally, mice tend to travel around 10 to 30 feet from their nestling. Ensure that the bait is fresh and free from contaminants like chemicals. Also, check the bait station and change it or replenish it regularly.

    Question: How do I prevent kids and pets from accessing the poisonous mouse bait?
    Answer: Use baiting stations with a lockable feature. This way, only targeted rodents will suffocate from eating the bait. Bait stations are tamper-resistant, durable, and can be attached to ensure that they are not moved or messed with.

    Question: Is one feeding enough for the mice to die?
    Answer: Killing mice is not an easy task. It depends on the type of mouse poison that you’re using. Different mouse poisons work in different ways. If it’s a first-generation anticoagulant, then you will have to feed the mice multiple times for it to be effective. But if it’s a second-generation anticoagulant, just one feed is enough for them to suffocate to death. Mice die quicker than rats as they are smaller, and the impact is far much stronger.

    If you still have any questions after reading our best mouse poisons review, then comment below.

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